Just over 15 years ago, a pseudoscientist named Iben Browning predicted that on December 3rd, 1990, a massive earthquake would hit the New Madrid fault in southeastern Missouri. The prediction caused mass hysteria. People bought earthquake insurance, news stations did stories about standing in doorways, and many of my classmates stayed home from school, "just in case."
The prediction, while silly and baseless, did bring something surprising to the attention of midwesterners: the largest earthquakes ever to hit the contiguous United States occurred along the New Madrid fault.
In 1811 and 1812, three earthquakes believed to be over 8.0 on the Richter scale occurred with epicenters in or near southeastern Missouri. They are said to have caused the Mississippi River to run backwards and were felt as far away as Massachusetts. Seismologists predict that another large earthquake will hit the area in the next few decades.
Want to read more? This is a site with a brief description of the New Madrid fault and links to eyewitness accounts of the 1811-1812 quakes. This is an article by a guy reflecting on the 1990 prediction hysteria. Want to read a lot more about Browning's prediction? The USGS will mail you a free 248-page report (!) about the incident.